Jonathan Clayton, DVM, Ph.D.
- Assistant Professor
- 523 Allwine Hall
AffiliationsAssistant Professor, Department of Biology, University of Nebraska-Omaha
Assistant Professor, Department of Food Science and Technology, University of Nebraska-Lincoln
Member, Callitrichid Research Center
Member, GreenViet Biodiversity Conservation Center
Founder, Primate Microbiome Project (PMP)
Teaching InterestsMicrobiology and Microbial Ecology
The Clayton Lab is studying host-microbiome interactions in humans and nonhuman primates. We are using nonhuman primates as a model for studying the effects of variations in dietary fiber and other dietary compounds, as well as lifestyle factors associated with modernized society, on the microbiome and metabolic health.
Dr. Clayton received his Doctor of Veterinary Medicine (D.V.M.) and his Doctor of Philosophy (Ph.D.) in Comparative and Molecular Biosciences from the University of Minnesota. For his Ph.D. thesis research, he used nonhuman primates as a model system for studying the effects of emigration and lifestyle disruption on the human gut microbiome. During his Ph.D., Dr. Clayton founded the Primate Microbiome Project (PMP) with the intended purpose to develop a systematic map of variation in microbiome structure and function across all primates and to relate this to primate health, evolution, behavior, and conservation.
The Clayton Lab are currently extending our research to explore in detail causal mechanisms for microbiome-modulated metabolic diseases including diabetes and obesity, as well as neurological/behavioral diseases such as stress. We do this using both in vitro and in vivo experiments, including, but not limited to, next-generation sequencing, anaerobic and aerobic culture, germ-free mouse models, and marmoset models.