Alexey V. Krasnoslobodtsev, PhD
- Isaacson Professor of Physics
- 402.554.3723
- Durham Science Center | Room 119
- Allwine Hall | Room 201B
Additional Information
Background
B.S., Novosibirsk State University, Novosibirsk, Russia
M.S., New Mexico State University, Las Cruces, NM
Ph.D., New Mexico State University, Las Cruces, NM
Dr. Krasnoslobodtsev joined the Department of Physics at UNO in August 2014, where he is currently a Professor. Dr. Krasnoslobodtsev teaches General Physics and specialized courses in the Biomedical Physics concentration. Dr. Krasnoslobodtsev's passion is doing research in the field of single-molecule biophysics. He improves and utilizes single-molecule biophysical techniques to primarily answer fundamental questions related to DNA-protein and protein-protein systems malfunctioning. Dr. Krasnoslobodtsev's laboratory currently has a Tethered Particle Motion setup, Single-molecule Fluorescence, Total Internal Reflection Fluorescence, Atomic Force Microscopes (AFM-workshop and Bruker Naoscope V), and a Raman spectrometer used to study the effects of Enhanced Raman Scattering and utilize these effects for biomedical applications.
Teaching
Primary teaching interests are in Biological and Medical Physics.
Courses taught:
Physical Pharmacy (Basics of Thermodynamics)
Gateway to Physics (Biological and Medical Physics)
Nanoimaging and Bioimaging (Single-molecule biophysical methods)
PHYS 1110 – General Physics I with Algebra
PHYS 1120 – General Physics II with Algebra
PHYS 2110 – General Physics I with Calculus
PHYS 2120 – General Physics II with Calculus
PHYS 3300 – Introduction to Biomedical Physics
PHYS 4500 – Biological Physics
PHYS 4550 – Medical Physics
Teaching statement: Dr. Krasnoslobodtsev strives to create a challenging and positive classroom environment that stimulates learning and student engagement.
Research Interests
Dr. Krasnoslobodtsev’s research interests lie at the interface of nanotechnology, biology, and physics. His research program uses principles of these disciplines to answer fundamental questions of biology that can facilitate early diagnostics and effective therapeutic solutions. He combines nanoimaging and nanomanipulation with spectroscopic techniques in his lab and develops hybrid biosensing nano-platforms with high sensitivity.
Recent Publications
10 most recent publications:
- Elizabeth Skelly, Christina J Bayard, Joel Jarusek, Benjamin Clark, Laura P Rebolledo, Yasmine Radwan, Phong Nguyen, Melanie Andrade-Muñoz, Thomas A Deaton, Alexander Lushnikov, Sharonda J LeBlanc, Alexey V Krasnoslobodtsev, Yaroslava G Yingling, Kirill A Afonin; Design and Characterization of DNA-Driven Condensates: Regulating Topology, Mechanical Properties, and Immunorecognition, ACS Applied Materials & Interfaces, 2025; 17(15), 22322-22336.
- Akhilesh Kumar Gupta and Alexey V. Krasnoslobodtsev; Nucleic-Acid Based Approaches for Detection of microRNA; RNA NanoMed, 2025, DOI: https://doi.org/10.59566/ISRNN.2025.0201A
- Akhilesh Kumar Gupta and Alexey V. Krasnoslobodtsev; Fueling the Future: The Emergence of Self-Powered Enzymatic Biofuel Cell Biosensors; Biosensors, 2024; 14(7), 316; https://doi.org/10.3390/bios14070316.
- Akhilesh Kumar Gupta, Nolan Marshall, Liam Yourston, Lewis Rolband, Damian Beasock, Leyla Danai, Elizabeth Skelly, Kirill A. Afonin, and Alexey V. Krasnoslobodtsev; Optical, structural, and biological properties of silver nanoclusters formed within the loop of C-12 hairpin sequence; Nanoscale Advances, 2023; 5, 3500 - 3511.
- Akhilesh Kumar Gupta and Alexey V. Krasnoslobodtsev; DNA-Templated Silver Nanoclusters as Dual-Mode Sensitive Probes for Self-Powered Biosensor Fueled by Glucose; Nanomaterials, 2023; 13(8), 1299. YEAR 2023 – EDITOR’S CHOICE.
- Shipra Solanki, Akhilesh Kumar Gupta, Udiptya Saha, Alexey V. Krasnoslobodtsev, Rajinder K. Gupta, Bansi D. Malhotra; Triboelectric Nanogenerator-based Smart Biomedical Sensors for Healthcare; Sustainable Energy Technologies and Assessments, 2023; 57, 103233.
- Dylan Fredrick, Liam Yourston, Alexey V. Krasnoslobodtsev, “Detection of cancer‐associated miRNA using fluorescence switch of AgNC@NA and guanine‐rich overhang sequences”. Luminescence, 2023; 1. https://doi.org/10.1002/bio.4471.
- Jamison Duckworth and Alexey Krasnoslobodtsev, “Modular Micro Raman Reader Instrument for Fast SERS-Based Detection of Biomarkers”. Micromachines, 2022, 13(10), 1570.
- Lewis Rolband, Liam Yourston, Morgan Chandler, Damian Beasock, Leyla Danai, Seraphim Kozlov, Nolan Marshall, Oleg Shevchenko, Alexey V. Krasnoslobodtsev, Kirill A. Afonin, “DNA-templated Fluorescent Silver Nanoclusters Inhibit Bacterial Growth while being Non-toxic to Mammalian Cells”, Molecules, 2021, 26(13), 4045.
- Xuejing Shen, Tao Sun, Lei Yang, Alexey Krasnoslobodtsev, Renat Sabirianov, Michael Sealy, Wai-Ning Mei, Zhanjun Wu, and Li Tan, “Ultra-fast Charging in Aluminum-Ion Batteries: Nanofeatures of the Electric Double Layers on Active Anode”, Nature Communications, 2021, 12, 820.
Synergetic Activities
Member of the Biophysical Society.
Member of The Nebraska Center for Materials and Nanoscience (NCMN).
Ad hoc Reviewer for 21 scientific journals.
Member of the Graduate Advising Committee (UNMC).
Member of the Premed Committee (UNO).
Mentoring research projects of undergraduate students.
Additional Information
Background
B.S., Novosibirsk State University, Novosibirsk, Russia
M.S., New Mexico State University, Las Cruces, NM
Ph.D., New Mexico State University, Las Cruces, NM
Dr. Krasnoslobodtsev joined the Department of Physics at UNO in August 2014, where he is currently a Professor. Dr. Krasnoslobodtsev teaches General Physics and specialized courses in the Biomedical Physics concentration. Dr. Krasnoslobodtsev's passion is doing research in the field of single-molecule biophysics. He improves and utilizes single-molecule biophysical techniques to primarily answer fundamental questions related to DNA-protein and protein-protein systems malfunctioning. Dr. Krasnoslobodtsev's laboratory currently has a Tethered Particle Motion setup, Single-molecule Fluorescence, Total Internal Reflection Fluorescence, Atomic Force Microscopes (AFM-workshop and Bruker Naoscope V), and a Raman spectrometer used to study the effects of Enhanced Raman Scattering and utilize these effects for biomedical applications.
Teaching
Primary teaching interests are in Biological and Medical Physics.
Courses taught:
Physical Pharmacy (Basics of Thermodynamics)
Gateway to Physics (Biological and Medical Physics)
Nanoimaging and Bioimaging (Single-molecule biophysical methods)
PHYS 1110 – General Physics I with Algebra
PHYS 1120 – General Physics II with Algebra
PHYS 2110 – General Physics I with Calculus
PHYS 2120 – General Physics II with Calculus
PHYS 3300 – Introduction to Biomedical Physics
PHYS 4500 – Biological Physics
PHYS 4550 – Medical Physics
Teaching statement: Dr. Krasnoslobodtsev strives to create a challenging and positive classroom environment that stimulates learning and student engagement.
Research Interests
Dr. Krasnoslobodtsev’s research interests lie at the interface of nanotechnology, biology, and physics. His research program uses principles of these disciplines to answer fundamental questions of biology that can facilitate early diagnostics and effective therapeutic solutions. He combines nanoimaging and nanomanipulation with spectroscopic techniques in his lab and develops hybrid biosensing nano-platforms with high sensitivity.
Recent Publications
10 most recent publications:
- Elizabeth Skelly, Christina J Bayard, Joel Jarusek, Benjamin Clark, Laura P Rebolledo, Yasmine Radwan, Phong Nguyen, Melanie Andrade-Muñoz, Thomas A Deaton, Alexander Lushnikov, Sharonda J LeBlanc, Alexey V Krasnoslobodtsev, Yaroslava G Yingling, Kirill A Afonin; Design and Characterization of DNA-Driven Condensates: Regulating Topology, Mechanical Properties, and Immunorecognition, ACS Applied Materials & Interfaces, 2025; 17(15), 22322-22336.
- Akhilesh Kumar Gupta and Alexey V. Krasnoslobodtsev; Nucleic-Acid Based Approaches for Detection of microRNA; RNA NanoMed, 2025, DOI: https://doi.org/10.59566/ISRNN.2025.0201A
- Akhilesh Kumar Gupta and Alexey V. Krasnoslobodtsev; Fueling the Future: The Emergence of Self-Powered Enzymatic Biofuel Cell Biosensors; Biosensors, 2024; 14(7), 316; https://doi.org/10.3390/bios14070316.
- Akhilesh Kumar Gupta, Nolan Marshall, Liam Yourston, Lewis Rolband, Damian Beasock, Leyla Danai, Elizabeth Skelly, Kirill A. Afonin, and Alexey V. Krasnoslobodtsev; Optical, structural, and biological properties of silver nanoclusters formed within the loop of C-12 hairpin sequence; Nanoscale Advances, 2023; 5, 3500 - 3511.
- Akhilesh Kumar Gupta and Alexey V. Krasnoslobodtsev; DNA-Templated Silver Nanoclusters as Dual-Mode Sensitive Probes for Self-Powered Biosensor Fueled by Glucose; Nanomaterials, 2023; 13(8), 1299. YEAR 2023 – EDITOR’S CHOICE.
- Shipra Solanki, Akhilesh Kumar Gupta, Udiptya Saha, Alexey V. Krasnoslobodtsev, Rajinder K. Gupta, Bansi D. Malhotra; Triboelectric Nanogenerator-based Smart Biomedical Sensors for Healthcare; Sustainable Energy Technologies and Assessments, 2023; 57, 103233.
- Dylan Fredrick, Liam Yourston, Alexey V. Krasnoslobodtsev, “Detection of cancer‐associated miRNA using fluorescence switch of AgNC@NA and guanine‐rich overhang sequences”. Luminescence, 2023; 1. https://doi.org/10.1002/bio.4471.
- Jamison Duckworth and Alexey Krasnoslobodtsev, “Modular Micro Raman Reader Instrument for Fast SERS-Based Detection of Biomarkers”. Micromachines, 2022, 13(10), 1570.
- Lewis Rolband, Liam Yourston, Morgan Chandler, Damian Beasock, Leyla Danai, Seraphim Kozlov, Nolan Marshall, Oleg Shevchenko, Alexey V. Krasnoslobodtsev, Kirill A. Afonin, “DNA-templated Fluorescent Silver Nanoclusters Inhibit Bacterial Growth while being Non-toxic to Mammalian Cells”, Molecules, 2021, 26(13), 4045.
- Xuejing Shen, Tao Sun, Lei Yang, Alexey Krasnoslobodtsev, Renat Sabirianov, Michael Sealy, Wai-Ning Mei, Zhanjun Wu, and Li Tan, “Ultra-fast Charging in Aluminum-Ion Batteries: Nanofeatures of the Electric Double Layers on Active Anode”, Nature Communications, 2021, 12, 820.
Synergetic Activities
Member of the Biophysical Society.
Member of The Nebraska Center for Materials and Nanoscience (NCMN).
Ad hoc Reviewer for 21 scientific journals.
Member of the Graduate Advising Committee (UNMC).
Member of the Premed Committee (UNO).
Mentoring research projects of undergraduate students.