WHEN:
Wednesday, October 18, 2006 at 2:30 PM
WHERE:
Durham Science Center, Room 256
WHAT:
ABSTRACT:
There is growing interest in understanding and controlling the spread
of diseases through realistically structured host populations.
I investigate how network structures, ranging from circulant,
through small-world networks, to random networks, and five
vaccination strategies, and vaccination effort interact to
influence the proportion of the population infected, the size
and timing of the epidemic peak, and the duration of the epidemic.
On average, vaccinating hosts based on degree (hubs) resulted
in the smallest epidemics while vaccinating hosts with the
highest clustering coefficient resulted in the largest epidemics.
Our model suggests how vaccinations might be implemented to minimize
the extent of an epidemic (e.g., duration and total number infected)
as well as the timing and number of hosts infected at a given time
over a wide range of realistically-structured host networks.
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