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Publications

Toxoplasma on the Brain: Understanding Host-Pathogen Interactions in Chronic CNS Infection. Kamerkar S, Davis PH. J. Parasitology Res. 2012 V2012:589295.

Targeted disruption of Toxoplasma gondii serine protease inhibitor 1 increases bradyzoite cyst formation in vitro and parasite tissue burden in mice. Pszenny V, Davis PH, Zhou XW, Hunter CA, Carruthers VB, Roos DS. Infect Immun. 2012 Mar;80(3):1156-65.

An insertional trap for conditional gene expression in Toxoplasma gondii: identification of TAF250 as an essential gene. Jammallo L, Eidell K, Davis PH, Dufort FJ, Cronin C, Thirugnanam S, Chiles TC, Roos DS, Gubbels MJ. Mol Biochem Parasitol. 2011 Feb;175(2):133-43.

A novel multifunctional oligonucleotide microarray for Toxoplasma gondii. Bahl A, Davis PH, Behnke M, Dzierszinski F, Jagalur M, Chen F, Shanmugam D, White MW, Kulp D, Roos DS. BMC Genomics. 2010 Oct 25;11:603.

Integrative genomic approaches highlight a family of parasite-specific kinases that regulate host responses. Peixoto L, Chen F, Harb OS, Davis PH, Beiting DP, Brownback CS, Ouloguem D, Roos DS. Cell Host Microbe. 2010 Aug 19;8(2):208-18.

Chemical genetics of Plasmodium falciparum. Guiguemde WA, Shelat AA, Bouck D, Duffy S, Crowther GJ, Davis PH, Smithson DC,Connelly M, Clark J, Zhu F, Jimenez-Diaz MB, Martinez MS, Wilson EB, Tripathi AK, Gut J, Sharlow ER, Bathurst I, El Mazouni F, Fowble JW, Forquer I, McGinley PL, Castro S, Angulo-Barturen I, Ferrer S, Rosenthal PJ, Derisi JL, Sullivan DJ, Lazo JS, Roos DS, Riscoe MK, Phillips MA, Rathod PK, Van Voorhis WC, Avery VM, Guy RK. Nature. 2010 May 20;465(7296):311-5.

Differences in the transcriptome signatures of two genetically related Entamoeba histolytica cell lines derived from the same isolate with different pathogenic properties. Biller L, Davis PH, Tillack M, Matthiesen J, Lotter H, Stanley SL Jr, Tannich E, Bruchhaus I. BMC Genomics. 2010 Jan 26;11:63.

Apicomplexan parasites co-opt host calpains to facilitate their escape from infected cells. Chandramohanadas R, Davis PH, Beiting DP, Harbut MB, Darling C, Velmourougane G, Lee MY, Greer PA, Roos DS, Greenbaum DC. Science. 2009 May 8;324(5928):794-7.

Proteomic comparison of Entamoeba histolytica and Entamoeba dispar and the role of E. histolytica alcohol dehydrogenase 3 in virulence. Davis PH, Chen M, Zhang X, Clark CG, Townsend RR, Stanley SL Jr. PLoS Negl Trop Dis. 2009;3(4):e415.

Estimating gene signals from noisy microarray images. Sarder P, Nehorai A, Davis PH, Stanley SL. IEEE Trans Nanobioscience. 2008 Jun;7(2):142-53.

Transcriptomic comparison of two Entamoeba histolytica strains with defined virulence phenotypes identifies new virulence factor candidates and key differences in the expression patterns of cysteine proteases, lectin light chains, and calmodulin. Davis PH, Schulze J, Stanley SL Jr. Mol Biochem Parasitol. 2007 Jan;151(1):118-28.

Comparative proteomic analysis of two Entamoeba histolytica strains with different virulence phenotypes identifies peroxiredoxin as an important component of amoebic virulence. Davis PH, Zhang X, Guo J, Townsend RR, Stanley SL Jr. Mol Microbiol. 2006 Sep;61(6):1523-32.

Coordinate but disproportionate activation of apoptotic, regenerative and inflammatory pathways characterizes the liver response to acute amebic infection. Pelosof LC, Davis PH, Zhang Z, Zhang X, Stanley SL Jr. Cell Microbiol. 2006 Mar;8(3):508-22.

Identification of a family of BspA like surface proteins of Entamoeba histolytica with novel leucine rich repeats. Davis PH, Zhang Z, Chen M, Zhang X, Chakraborty S, Stanley SL Jr. Mol Biochem Parasitol. 2006 Jan;145(1):111-6.

Breaking the species barrier: use of SCID mouse-human chimeras for the study of human infectious diseases. Davis PH, Stanley SL Jr. Cell Microbiol. 2003 Dec;5(12):849-60.