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Neuroscience Program
Neuroscience Program

Erin Young

 

 

 

 

 

Erin L. Young, Ph.D.

 

Education

2005  Ph.D.  Experimental (Biological) Psychology, Kent State University
Dissertation title:  The Neonatal Injury Induced Learning Deficit in Adult Spinal Rats:  Characterization of Induction and Maintenance

2003  M.A. Experimental (Biological) Psychology, Kent State University
Thesis title:  Lipopolysaccharide Disrupts Acquisition of a Flexion Response in Spinal Rats

2000  B.A. Biology (minors in Physics and Neuroscience), Wesleyan College (GA)

 

Academic Positions

2011 Research Assistant Professor, Department of Anesthesiology, University of
Pittsburgh School of Medicine

6/2011-10/2011 Research Scholar, Department of Anesthesiology, University of Pittsburgh School of Medicine

2008-2011 Assistant Research Scientist, Behavioral and Cellular Neuroscience Program, Department of Psychology, Texas A&M University   

2005-2008 Postdoctoral Research Associate, Behavioral and Cellular Neuroscience Program, Department of Psychology, Texas A&M University

2001-2005 Graduate Research Assistant/Teaching Fellow, Department of Psychology, Kent State University

 

Publications

Baumbauer, KM, Young, EE, Hoy, K, France, J, & Joynes, RL. (2006).  Intrathecal infusions of     anisomycin impact the learning deficit but not the learning effect observed in spinal rats that have received instrumental training.  Behavioural Brain Research, 173(2), 299-309.

Baumbauer, KM, Young, EE, Hoy, KC, Abood, A, & Joynes, RL.  (2007).  Administration of a calcium/calmodulin-dependent protein kinase II (CaMKII) inhibitor reverses the noncontingent shock learning deficit observed in spinal rats. Behavioral Neuroscience, 121(3), 570-578. 

Baumbauer, KM, Young, EE, Hoy, KC, Jr, & Joynes, RL.  (2007).  Intrathecal administration of neurokinin 1 and neurokinin 2 receptor antagonists undermines the savings effect in spinal rats seen in an instrumental learning paradigm.  Behavioral Neuroscience, 121(1), 186-199.

Baumbauer, KM, Young, EE, Hoy, KC, Jr, & Joynes, RL.  (2007).  Neurokinin receptors modulate the impact of uncontrollable shock on spinal plasticity.  Behavioral  Neuroscience, 121(5), 1082-1094.

Meagher, MW, Johnson, RR,Vichaya, EG, Young, EE, Lunt, S & Welsh, CJR.  (2007).  Social  conflict exacerbates an animal model of multiple sclerosis.  Trauma, Violence, and    Abuse, 8(3), 314-330. 

Meagher, MW, Johnson, RR, Young, EE, Good, E,  Lunt, SC, Hardin, EA, Connor, MA,  Welsh, TH, & Welsh, CJR.  (2007).  IL-6 as a mechanism for the effects of SDR on acute TMEV infection.  Brain, Behavior and Immunity, 21(8), 1083-1095. 

Young, EE, Baumbauer, KM, Elliot, A, & Joynes, RL. (2007).  Lipopolysaccharide induces a  spinal learning deficit that is blocked by IL-1 receptor antagonism.  Brain, Behavior, and Immunity, 21(6), 748-757.     **Highlighted by the editor for” carrying new and novel insights” in the 8/07 issue of BBI and accompanied by an invited commentary by Dr. Terence Deak.

Young, EE, Baumbauer, KM, Elliot, A, & Joynes, RL. (2007). The impact of neonatal injury on spinally mediated instrumental learning in adult rats.    Behavioral Neuroscience, 121(5), 1095-1100.

Young, EE, Baumbauer, KM, Hillyer, JE, & Joynes, RL.  (2007).  Local anesthetic treatment significantly attenuates acute pain responding but does not prevent the neonatal injury-     induced reduction in adult spinal behavioral plasticity.  Behavioral Neuroscience, 121(5),         1073-1081.

Young, EE, Baumbauer, KM, Hillyer, JE, Patterson, AM, Hoy, KC Jr, Mintz, EM, & Joynes, RL.  (2008).  The neonatal injury-induced spinal learning deficit in adult rats:  Central   mechanisms.  Behavioral Neuroscience, 122(3), 589-600

Young, EE, Prentice, TW, Satterlee, D, McCullough, H, Sieve, AN, Johnson, RR, Welsh, T, Welsh, CJR, & Meagher, MW.  (2008).  Glucocorticoid exposure alters the pathogenesis of Theiler’s murine encephalomyelitis virus during acute infection.  Physiology and Behavior, 95, 63-71. 

Grimes, JS, Creech SK, Young EE, Vichaya EG & Meagher MW.  (2009).  Distraction speeds the decay of fear-induced hyperalgesia:  Evidence for the contribution of memorial systems in affective pain modulation.  Journal of Pain, 10(3), 282-292.     

Baumbauer, KM, Young, EE & Joynes, RL.  (2009). Pain and learning
in a spinal system:  Contradictory outcomes from common origins.  Brain Research Reviews, 61(2), 124-143. 

Young EE, Sieve AN, Vichaya EG, Carcoba LM, Young CR, Ambrus A, Storts R, Welsh CJR& Meagher MW.  (2010).  Chronic restraint stress during early Theiler’s virus infection exacerbates the subsequent demyelinating disease in SJL mice:  Histological evaluation of CNS disease severity.  Journal of Neuroimmunology, 220 (1-2), 79-89.

Vichaya EG, Young EE, Frazier MA, Cook JL, Welsh CJ, & Meagher MW.  (2011).  Social disruption induced priming of CNS inflammatory response to Theiler's virus is dependent upon stress-induced IL-6 release.  Journal of Neuroimmunology 239(1-2), 44-52.

Young EE, Lariviere WR, & Belfer, I.  (2012).  Genetic basis of pain variability:  Recent Advances.  Journal of Medical Genetics 49(1), 1-9.   
**This article was #7 of Medscape’s Most-Read Journal Articles by Anesthesiologists, featured as one of the most popular full-text, peer-reviewed journal articles from hundreds of publications and key societies in February and April 2012. 

Young EE, Vichaya EG, Cook JL, Reusser N, Welsh CJR, & Meagher MW.  (2012).  Chronic social stress impairs virus specific adaptive immunity during acute Theiler's virus infection.  Journal of Neuroimmunology.  http://www.sciencedirect.com/science/article/pii/S016557281200272X 

 

Published Abstracts

Young, EE and Joynes, RL. (2002).  Lipopolysaccharide Administration Disrupts Acquisition of     an Increased Flexion Response in Adult Spinal Rats. Annual meeting of the Society for Neuroscience, Orlando, FL.

Baumbauer, KM, Hoy, KC, France, J, Young, EE, & Joynes, RL. (2003). The
impact of intrathecal protein synthesis inhibition on an acquired flexion response     in  spinal rats. Annual meeting of the Society for Neuroscience, New Orleans, LA.

Baumbauer, KM, Young, EE, Hoy, K, France, J, & Joynes, RL. (2003).  The role of protein synthesis inhibition in the acquired flexion response in spinal rats.  Annual meeting of the Pavlovian Society, Bloomington, IN.

Young, EE, Baumbauer, KM, Elliott, A, & Joynes, RL. (2003). NOS inhibitor does not prevent lipopolysaccharide (LPS) induced disruption of instrumental learning in spinal rats.Annual meeting of the Society for Neuroscience, New Orleans, LA.

Young, EE, Baumbauer, KM, Elliott, A, & Joynes, RL. (2003). The impact of
neonatal injury on spinally mediated instrumental learning in adult rats. Annual meeting of the Pavlovian Society, Bloomington, IN.

Baumbauer, KM, Young, EE, Hoy, KC, and Joynes, RL.  (2004).  The role of calcium/calmodulin kinase II (CAMKII) in the maintenance of the learning deficit   observed in spinal rats. Annual meeting of the Society for Neuroscience, San Diego, CA.

Brown, JE, Young, EE, Baumbauer, KM, Elliott, AE, and Joynes, RL.  (2004).  The impact of supraspinal systems on the developmental of spinal plasticity in rats after neonatal hindpaw injury. Annual meeting of the Society for Neuroscience, San Diego, CA.

Young, EE, Baumbauer, KM, and Joynes, RL.  (2004).  The role of nitric oxide in the learning deficit observed after noncontingent shock in adult spinal rats. Annual meeting of the Society for Neuroscience, San Diego, CA.

Baumbauer, KM, Hoy, KC, Young, EE, and Joynes, RL.  (2005).  Intrathecal administration of  NK1 receptor antagonist L-703,606 undermines the savings effect and reverses the learning deficit observed in spinally mediated instrumental learning.  Annual meeting for   the Society for Neuroscience, Washington, DC.

Hillyer, JE, Young, EE, Wallace, S, and Joynes, RL.  (2005).  Are supraspinal
systems necessary for the development of injury-induced sensitization in the
neonatal rat?  Annual meeting of the Society for Neuroscience, Washington, DC. 

Hoy, KC, Baumbauer, KM, Young, EE, Riccio, DC, and Joynes, RL.  (2005).
Direct stimulation of NK-1 and NK-2 receptors disrupts acquisition of a flexion
response in spinal rats.  Annual meeting for the Society of Neuroscience, Washington, DC. 

Young, EE, Baumbauer, KM, Hillyer, JE, and Joynes, RL.  (2005).  Lidocaine
administration does not prevent the neonatal injury-induced deficit in adult spinal
learning.  Annual meeting for the Society for Neuroscience, Washington, DC.

Young, EE and Joynes, RL.  (2005).  Characterization of the pathway involved in the neonatal injury induced learning deficit in adult spinal rats.  Paper presented at the annual    meeting of the Midwestern Psychological Association, Chicago, IL 

Young, EE, Good, E, Copeland, S, Johnson, RR, Welsh, CJ, and Meagher, MW. (2006).  The role of glia in the exacerbating effects of social stress on acute Theiler’s virus (TMEV) infection.  Annual meeting of the Society for Neuroscience, Atlanta, GA.

Young, EE, Vichaya, E, and Meagher, MW.  (2007).  Prior exposure to chronic social stress  sensitizes zymosan-induced mechanical allodynia.  Annual meeting of the Society for Neuroscience, San Diego, CA.  

Young, EE, Sieve AN, Vichaya EG, Carcoba LM, Steelman AJ, Young CR, Ambrus A, Storts R, Welsh TH, Welsh CJR, and Meagher MW.  (2008).  Impact of chronic restraint stress    during early Theiler's virus infection on CNS disease severity in SJL mice.  Annual meeting of the Psychoneuroimmunology Research Society, Madison, WI.     

Young EE, Sieve AN, Vichaya EG, Carcoba LM, Steelman AJ, Young CR, Ambrus A, Storts R, Welsh CJR, and Meagher MW.  (2008).  Chronic restraint stress during early Theiler’s virus infection exacerbates the subsequent demyelinating disease in SJL mice:  II. Histological evaluation of CNS disease severity.  Annual meeting of the Society for Neuroscience, Washington, DC. 

Herrman JW, Young EE, and Meagher MW.  (2009).  Chronic social stress sensitizes inflammatory arthritis in the mouse.  Texas A&M Society for Neuroscience Symposium.   

Vichaya EG, Young EE, and Meagher MW.  (2009).  Chronic social disruption stress facilitates zymosan-induced mechanical allodynia.  Texas A&M Society for Neuroscience  Symposium.

Vichaya EG, Young EE, and Meagher MW.  (2009).  Chronic social disruption stress facilitates       zymosan-induced mechanical allodynia.   Annual meeting of the  Psychoneuroimmunology Research Society, Breckenridge, CO.   

Frazier MA, Vichaya EG, Young EE, Welsh CJR, and Meagher MW.  (2009).  Prior exposure to social stress sensitizes virus-induced cytokine expression during acute Theiler's virus infection.  Texas A&M Society for Neuroscience Symposium. 

Frazier MA, Vichaya EG, Young EE, Welsh CJR, and Meagher MW.  (2009).  Prior exposure to social stress sensitizes virus-induced cytokine expression during acute Theiler's virus infection.  Annual meeting of the Psychoneuroimmunology Research Society,  Breckenridge, CO.

Young EE, Herrman JW, Vichaya EG, and Meagher MW.  (2009).  Chronic social stress exacerbates inflammatory arthritis-induced pain.  Annual meeting of the Society for Neuroscience, Chicago, IL, 76.17.  

Vichaya EG, Cook JL, Frazier MA, Young EE and Meagher MW. (2010). Modeling symptoms of chemotherapy: Bortezomib and 5-Fluorouracil induce sickness in mice. Psychoneuroimmuology Research Society, Dublin, Ireland, June 2010.

Vichaya EG, Cook JL, Frazier MA, Young EE & Meagher MW. (2010). Modeling symptoms of chemotherapy: Bortezomib induce sickness in mice.  Annual meeting of the Society for Neuroscience, San Diego, CA, 361.10.

Young EE, Vichaya EG, Cook JL, Reusser NM, Welsh CJR and Meagher MW.  (2010). Social stress disrupts virus-specific adaptive immunity during acute Theiler’s virus infection.  Annual meeting of the Society for Neuroscience, San Diego, CA, 359.7. 

Bouchard SM, Young EE, Vichaya EG, Cook JL and Meagher MW.  (2011).
Characterization of Sickness Behavior Induced by the Colorectal Chemotherapy Agents Oxaliplatin and 5-FU.  Annual meeting of the Psychoneuroimmunology Research Society, Chicago, IL. 

Bouchard SM, Young EE, Vichaya EG, Cook JL and Meagher MW.  (2011).  Cancer chemotherapy-induced sickness behavior is associated with increased peripheral and central cytokine expression.  Annual meeting of the Society for Neuroscience, Washington, DC, 87. 

Young EE, D’Ardenne CA, and Lariviere WR.  (2012).  Identification of novel candidate genes for inflammation-induced hypersensitivity and hyposensitivity. International Association for the Study of Pain, Milan, IT.

Lariviere WR, Young EE, Benhayon D, Kirshner M, Coates MD, Davis BM and Szigethy E.  (2013).  Genome-wide expression profiling of brain areas involved in pain processing and depression in a mouse model of inflammatory bowel disease. Winter Conference on Brain Research, Breckenridge, CO.