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Richard Lomneth

Contact Information:
Durham Science Center 349
Phone : (402) 554-3097
Dept Fax : (402) 554-3888
E-mail : rlomneth@mail.unomaha.edu

Education:
Ph.D. University of Cincinnati, 1988
B.S. Virginia Polytechnic Institute and State University 1978

Current Research:
p-Glycoprotein

Publications:
Puffer, E.B., Lomneth,R.B., Sarkar, H.K. and Singh, B.R. (2001) Differential Roles of Developmentally Distinct SNAP-25 Isoforms in Neurotransmitter Release Process. Biochemistry, 40, 9374-9378.

Marsh, R.S., Moe, C., Lomenth, R.b>, Fawcett, J.D. and Place, A.R. (2001) Characterization of gastrointestinal chitinase in the lizard Sceloporus undulatus garmani (Reptilia: Phrynosomatidae). Comparative Biochemistry and Physiology Part B, 128, 675-682.

Fu, F., Lomenth, R., Cai, S. and Singh, B.R. (1998) Role of zinc in the structure and toxic activity of botulinum neurotoxin. Biochemistry, 37, 5267-5278.

Gimenez, J., Lomneth, R. and DasGupta, B.R. (1994) Clostridium Butyricum neurotoxin: partial amino acid sequence of major proteolytic fragments and intracellular activity in PC12 cells. Toxicon, 32, 1137-1146.

Lomneth, R., Gimenez J., Martin T.F.J. and DasGupta, B.R. (1993) Ca2+ -dependent norepinephrine release from permeablizied PC12 cells is inhibited bt ~48 and ~112 kDa fragments of botulinum neurotoxin type E. Neuropharmacology, 32, 285-289

Publications Continued:
Lomneht, R., Martin, T.F.J. and DasGupta, B.R. (1991) Botulinum neurotoxin light chain inhibits norepinephrine secretion in PC12 cells at an intracellular membranous or cytoskeletal site. K. Neurochem. 57, 1413-1421.

Lomneth, R., Suszkiw, J. and DasGupta, B.R. (1990) Response of the chick ciliary ganglion-iris neuromuscular preparation to botulinum neurotoxin. Neurosci. Lett. 113, 211-216.

*Lomneht, R., Medrano, S. and Gruenstein, E.I. (1990) The role of transmembrane pH gradients in the lactic acid induced swelling of astrocytes. Brain Res. 532, 69-77.

Lomenth, R. and Gruenstein, E.I. (1989) Engergy-dependent cell volume maintenance in UC-11MG human astrocytomas. Am. J. Physiol. 257, C817-C824.

Lomneth, R., Bkaily, G., Sperelakis, N., Liwnicz, B.H. and Gruenstein, E. (1989) Electrophysiological and biochemical characterization of a continuous human astrocytoma cell line with many properties of well-differentiated astrocytes. Brain Res. 486, 95-107.

*Recogition by the editors of "Cerebrovascular and Brain Metabolism Reviews" as a paper of "of particular interest and importance."

Invited Interviews :
Lomenth, R. (1999) Inhinbition of exocytosis by botulinum neurotoxins aids the understanding of exocytotic mechanisms in many different cell types. Journal of Toxicology - Toxin Reviews, 18, 77-94.

Patents:
Blair, D.B., Lomneth, R.B., Prosise, R.L., and Tao, B.Y., inventors; Procter & Gamble Co., assignee. Margarine oil products. U.S. patent 4,390,561. 1983 June 28.

Lomneth, R.B., Blair, D.B., Parnell, G.L. and Tao, B.Y., inventors; Procter & Gamble Co., assignee. Margarine and method for making same. U.S. patent 4,388,339. 1983 June 14.