UNO Spirit

additional resources.

Ronald Bartzatt

Contact Information:
Durham Science Center 334
Phone : (402) 554-3612
Dept Fax : (402) 554-3888
E-mail : rbartzatt@mail.unomaha.edu

Education:
B.S. University of Nebraska 1978
M.S. University of Nebraska 1980
Ph.D. University of Nebraska 1982

Current Research:
Medicinal Chemistry
Analytical Chemistry
Drug Design and Development

Publications:
R. Bartzatt, S. Cirillo, J. Cirillo, L. Donigan, Bifunctional constructs of
aspirin and ibuprofen (non-steroidal anti-inflammatory drugs; NSAIDS)
that express antibacterial and alkylation activity. Biotechnology and
Applied Biochemistry 2003, 37;273-282.

R. Bartzatt, Synthesis and alkylation activity of a nitrogen mustard
agent to penetrate the blood-brain barrier. Drug Delivery (accepted
2003), 2004, 11;1-8.

R. Bartzatt, C. Malesa, Synthesis, structural analysis and antibac-
terial activity of a butyl ester derivative of ampicillin. Chemotherapy
2003, 49;213-221.

4. R. Bartzatt, Two lead drug designs based on chloramphenicol as the
parent structure, which express alkylation activity with potential for clinical
applications. J. Of Pharmacy and Pharmacology, 2003, 55;653-660.

R. Bartzatt, L. Donigan, Two identical twin nitrogen mustard agents that
express rapid alkylation activity at physiological pH 7.4 and 37 C.
Letters in Drug Design & Discovery (accepted 2003) 2004, 1:1-5.

R. Bartzatt, L. Donigan, A bifunctional alkylating nitrogen mustard
agent that utilizes barbituric acid as carrier drug with the potential for
crossing the brain-blood barrier. Receptors and Channels 2003, 9;
309-313.

R. Bartzatt, Synthesis and activity of an anti-neoplastic aromatic
nitrogen mustard agent that alkylates nucleophiles at 37 C and pH 7.4.
Preclinica 2003, 1(3);127-132.

R. Bartzatt, Dansylation of aromatic, aliphatic, and medicinal carboxylic
acid compounds in 1 M Na2CO3 buffer. Analytica Chimica Acta 2003,
488;203-209.

C. Malesa, J. Stoddard, R. Bartzatt, Utilizing structure property correla-
tions to predict and analyze two derivatives of an ampicillin homologous
series. Journal of Undergraduate Chemistry Research 2003, 2(4);127-134.